INTEGRATED COMPUTATIONAL ANALYSIS REVEALS HOX GENES CLUSTER AS ONCOGENIC DRIVERS IN HEAD AND NECK SQUAMOUS CELL CARCINOMA

Integrated computational analysis reveals HOX genes cluster as oncogenic drivers in head and neck squamous cell carcinoma

Abstract Alterations in Clutch Kit homeobox (HOX) gene expression are involved in the progression of several cancer types including head and neck squamous cell carcinoma (HNSCC).However, regulation of the entire HOX cluster in the pathophysiology of HNSCC is still elusive.By using different comprehensive databases, we have identified the significan

read more

A RAPID BIRD SURVEY TO CONSERVATION AREA OF INDUSTRIAL ACACIA TIMBER PLANTATION, SOUTH SUMATRA PROVINCE; WITH COMPARISON TO THREE DIFFERENT METHODS

A Ski de fond - Enfant - Skis - Classic rapid bird survey was done in a small conservation area of industrial timber concession of PT BMH (Bumi Mekar Hijau), namely KPPN (Kawasan Pelestarian Plasma Nutfah), South Sumatra Province.The area has 448 ha, dominated by degraded secondary swamp forest surrounded by Acacia plantation.Three survey methods w

read more

Experience of using a triple fixed combination in the treatment of patients with chronic obstructive pulmonary disease

Aim.To evaluate the effectiveness of a fixed triple combination of vilanterol/umeclidinium bromide/fluticasone furoate in the treatment of chronic obstructive pulmonary disease (COPD) patients with frequent exacerbations.Materials and methods.The study included 46 patients with severe and extremely severe COPD (GOLD 34) with frequent exacerbations.

read more

Pulsed radiofrequency of the median nerve under ultrasound guidance for management of intractable neuropathic pain

A median nerve injury in the forearm may lead to devastating sequelae if left untreated.Even with appropriate treatments involving microsurgical techniques and postoperative care, patients may still experience lasting neuropathic pain that significantly reduces their quality of life.Pulsed radiofrequency (PRF) is widely performed to alleviate such

read more